Mercedes-Benz · Midsize cars · Plug-in hybrid
Mercedes-Benz E-Class Plug-in hybrid: MPG and annual fuel cost, 2026
Rated at 24 MPG combined for 2026, the Mercedes-Benz E-Class Plug-in hybrid is 24th of 31 midsize cars, in the bottom quarter.
- 24MPG combined24th of 31 in class
- $3,400a year in fuel24th of 31 in class
- 115g/mile CO2
Where it stands
The midsize cars rated for 2026 run from 14 to 139 MPG, with a median of 30 MPG.
Among all plug-in hybrid models of the year, regardless of size, it is tied for 14th of 29 plug-in hybrid models, in the upper half.
Within the 22 Mercedes-Benz models rated for 2026 it is 12th on combined rating; the median of the make's line-up is 25.5 MPG.
In its class, just ahead of it is the BMW 5 Series Plug-in hybrid at 25 MPG and just behind it is the Audi A6 at 23 MPG.
A plug-in hybrid can run on its battery for a distance and then on fuel. The MPG, fuel cost and CO2 figures on this site are for running on fuel with the battery depleted, so a driver who charges often will use less fuel than shown.
Fuel cost and CO2
The file prices the fuel for its most efficient version at about $3,400 a year, assuming 15,000 miles a year with 55% of them in the city and premium gasoline at $5.48 per gallon. That is $900 more than the midsize cars median of $2,500.
It emits 115 g of CO2 per mile from the tailpipe; the midsize cars median is 269, a difference of 154 g/mile.
Rated versions
Its city rating is 22 and its highway rating 27: the highway figure is 5 higher. 2 versions are rated for 2026. The most efficient, AMG E53 Hybrid 4matic Plus: 3.0 L, 6 cyl hybrid, Automatic 9-spd, AWD, gets 24 MPG; the least efficient listed, AMG E53 Hybrid 4matic Plus (station wagon): 3.0 L, 6 cyl hybrid, Automatic 9-spd, AWD, gets 22 MPG, a gap of 2 MPG. With the file's assumptions that gap is worth about $350 a year in fuel.
| Version | Combined MPG | City MPG | Highway MPG | Annual fuel cost | CO2 g/mile | Electric range |
|---|---|---|---|---|---|---|
| AMG E53 Hybrid 4matic Plus: 3.0 L, 6 cyl hybrid, Automatic 9-spd, AWD | 24 | 22 | 27 | $3,400 | 115 | 44 |
| AMG E53 Hybrid 4matic Plus (station wagon): 3.0 L, 6 cyl hybrid, Automatic 9-spd, AWD | 22 | 21 | 25 | $3,750 | 127 | 41 |
Year by year
The Mercedes-Benz E-Class Plug-in hybrid is in the data for 2 of the 8 model years from 2019 to 2026. Between 2025 and 2026 the best combined rating rose by 1 MPG, from 23 to 24. The number of rated versions grew from 1 to 2. Fuel cost for the best version is $3,400 in the latest data against $3,550 in 2025, although the file applies today's fuel prices to every model year, so that change comes from the rating, not from prices.
| Model year | Versions | Best MPG | Lowest MPG | Fuel cost | CO2 g/mi | Class median |
|---|---|---|---|---|---|---|
| 2026 | 2 | 24 | 22 | $3,400 | 115 | 30 |
| 2025 | 1 | 23 | 23 | $3,550 | 117 | 29 |
Similar models
| Model | Powertrain | Combined MPG | Annual fuel cost | Model year |
|---|---|---|---|---|
| BMW 5 Series Plug-in hybrid | Plug-in hybrid | 25 | $3,300 | 2026 |
| Audi S5 | Gasoline | 23 | $3,550 | 2026 |
| Cadillac CT5 | Gasoline | 26 | $3,150 | 2026 |
| Subaru WRX | Gasoline | 22 | $3,750 | 2026 |
| Alfa Romeo Giulia | Gasoline | 27 | $3,050 | 2026 |
Compare and rank
Rankings: Midsize cars, Plug-in hybrid, Mercedes-Benz.
Data: US EPA and DOE, as prepared in methods and data.